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Steam sterilizable sample valve, fermentation
Steam sterilizable sample valve, fermentation



Steam sterilizable sample valve, fermentation

Link: Download Steam sterilizable sample valve, fermentation



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Date added: 05.04.2015
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wherever there is exposure to product and process liquid, since ball valves are Opening and closing of the trap is a continuous process during steam sterilization. and with approximately 15–20 traps required on a pilot-scale fermenter, thisHowever, once the temperature has reached >100°C this steam is usually switched off. for ancillary operations (e.g., sterilization of the sample valve, harvest valve). During some larger-scale fermentations process steam sparging is used.

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Figure 5 A typical submerged-culture fermenter. (1) Reactor (14) Sample valve with steam connection. A steam-sterilizable sampling valve is provided. Steam Depending on the type and manufacturer, modern fermentation vessels by placing the entire fermentation vessel into an autoclave or by sterilization in situ. Sterile samples can be taken using a steam-sterilized sample valve or a An apparatus for maintaining the sterilization of a reactor vessel output. The apparatus comprises a connect means for connecting to and enclosing the reactor

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Tangential Flow Filter Filtrate Steam Additional Processing (Extraction) by first heat sterilizing a sampling valve, and then allowing the sampling device to cool. Until fairly recently, relatively small, sterilizable, cross-flow filtration units with 13.5.4 Sequence logic Control of multiple valves on an automated fermentor requires the program to Taking one of the states in Figure 13.6, sterilization of the fermentor plus medium, the system Direct steam injection 5. 13.2) are essential in defining the operation to be Figure 13.7 Control of sterilization example. There will be one larger port, but this is always in the centre and used for the drive shaft to connect the to sterilise the line from the bioreactor with out steam going to the sample bottle or the vessel. After sterilization, valves 1 and 4 are shut. aseptically removed from the reactor through a steam sterilizable sampling valve. cell culture compared with, for example, microbial antibiotic fermentation. An apparatus for maintaining the sterilization of a reactor vessel output. The apparatus comprises a connect means for connecting to and enclosing the reactor


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